MetaPanG

Note

MetaPanG is under active development.

MetaPanG is a tool for strain-level profiling of metagenomic samples against bacterial pangenome graphs. Given sequencing reads and a collection of species pangenomes, it detects the species present in a sample, maps the reads onto each species pangenome, and resolves the mixture of strains together with their relative abundances and per-strain gene content.

MetaPanG relies on PanGBank, a database of precomputed bacterial pangenomes accessed through a web API. For each species, PanGBank provides the pangenome together with the additional data structures that MetaPanG requires.

The files needed for a run are downloaded from PanGBank on demand and cached locally, so each resource is retrieved only once and reused by later runs.

See Installation for the supported setups, and Usage for a walkthrough.